Sepsis

Sepsis is the most deadly and costly hospital condition to treat today1

  • Over 1.6M are diagnosed with sepsis and over 250,000 die each year in the US1
  • Approximately $24 Billion spent annually at an average cost per hospital stay of $18,4001
  • Survivors risk physical and cognitive impairment and more-than-doubled the risk of dying within 5 years2

Challenges in Sepsis Diagnosis

Reducing time to appropriate antimicrobial treatment improves outcomes1

  • 80% of sepsis deaths could be prevented with rapid diagnosis and treatment1
  • Diagnosis today is a multi-step process that takes 1 to 5 days to pathogen ID and appropriate or optimal antimicrobial therapy3
  • 30%-45% of sepsis patients receive inappropriate initial antimicrobial therapy4,5
  • Every hour delay of appropriate antimicrobial treatment increases morbidity and mortality associated with sepsis4

Every hour of delay in appropriate intial therapy increases mortality of 7.6% associated with severe sepsis4

Worldwide sepsis affects over 26 million each year1 with average mortality rates from 16 - 40%6

Sepsis causes > 250,000 deaths1 with $23.7 Billion costs per year in the US7

Sepsis mortality in Europe is 10-15% higher than it is in the US8

Sepsis is the #1 cause of readmissions to the hospitals in the US costing more than $2 billion each year1

Qvella Has a Solution

Uniquely designed to provide unprecedented, fully automated pathogen identification directly from whole blood in minutes

Qvella's FAST-IDTM BSI Panel system is uniquely engineered to deliver the rapid results healthcare providers need to initiate earlier tailored antimicrobial therapy in the management of sepsis.

1Kumar et al. (2015). Empiric Antimicrobial Therapy in Severe Sepsis and Septic Shock: Optimizing Pathogen Clearance. Curr Infect Dis Rep.,17(7), 493.

2Derek C. Angus, M.D., M.P.H., and Tom van der Poll, M.D., Ph.D., (2013), Severe Sepsis and Septic Shock, N Engl J Med 2013; 369:840-851.

3Konrad Reinhart et al, (2012). New Approaches to Sepsis: Molecular Diagnostics and Biomarkers. Clin Microbiol Rev. 2012 Oct; 25(4): 609–634.

4Sepsis Alliance (2016, November) Sepsis 2016 fact sheet Retrieved from https://www.sepsis.org/downloads/2016_sepsis_facts_media.pdf

5Opota, O., Jaton, K., & Greub, G. (2015). Microbial diagnosis of bloodstream infection: towards molecular diagnosis directly from blood. Clinical Microbiology And Infection, 21(4), 323-331.

6Hospital Incidence and Mortality Rates of Sepsis (2016, March) Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814768/